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Galectin 3 Deficiency Alters Chondrocyte Primary Cilium Formation and Exacerbates Cartilage Destruction via Mitochondrial Apoptosis

Mechanical overload and aging are the main risk factors of osteoarthritis (OA). Galectin 3 (GAL3) is important in the formation of primary cilia, organelles that are able to sense mechanical stress. The objectives were to evaluate the role of GAL3 in chondrocyte primary cilium formation and in OA in...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Hafsia, Narjès, Forien, Marine, Renaudin, Félix, Delacour, Delphine, Reboul, Pascal, Van Lent, Peter, Cohen-Solal, Martine, Lioté, Frédéric, Poirier, Françoise, Ea, Hang Korng
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073077/
https://ncbi.nlm.nih.gov/pubmed/32098291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041486
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