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The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts

Activating transcription factor-6 α (ATF6) is one of the three main sensors and effectors of the endoplasmic reticulum (ER) stress response and, as such, it is critical for protecting the heart and other tissues from a variety of environmental insults and disease states. In the heart, ATF6 has been...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Stauffer, Winston T., Blackwood, Erik A., Azizi, Khalid, Kaufman, Randal J., Glembotski, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073073/
https://ncbi.nlm.nih.gov/pubmed/32085622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041373
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