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Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence

A major challenge in treating cancer is posed by intratumor heterogeneity, with different sub-populations of cancer cells within the same tumor exhibiting therapy resistance through different biological processes. These include therapy-induced dormancy (durable proliferation arrest through, e.g., po...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Mirzayans, Razmik, Murray, David
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073004/
https://ncbi.nlm.nih.gov/pubmed/32075223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041308
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