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Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence

A major challenge in treating cancer is posed by intratumor heterogeneity, with different sub-populations of cancer cells within the same tumor exhibiting therapy resistance through different biological processes. These include therapy-induced dormancy (durable proliferation arrest through, e.g., po...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mirzayans, Razmik, Murray, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073004/
https://ncbi.nlm.nih.gov/pubmed/32075223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041308
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