RhoA/ROCK Regulates Prion Pathogenesis by Controlling Connexin 43 Activity

Scrapie infection, which converts cellular prion protein (PrP(C)) into the pathological and infectious isoform (PrP(Sc)), leads to neuronal cell death, glial cell activation and PrP(Sc) accumulation. Previous studies reported that PrP(C) regulates RhoA/Rho-associated kinase (ROCK) signaling and that...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kim, Hee-Jun, Kim, Mo-Jong, Mostafa, Mohd Najib, Park, Jeong-Ho, Choi, Hong-Seok, Kim, Yong-Sun, Choi, Eun-Kyoung
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072953/
https://ncbi.nlm.nih.gov/pubmed/32070020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041255
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker