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Establishment and Characterization of a Brca1(−/−), p53(−/−) Mouse Mammary Tumor Cell Line

Breast cancer is the most commonly occurring cancer in women and the second most common cancer overall. By the age of 80, the estimated risk for breast cancer for women with germline BRCA1 or BRCA2 mutations is around 80%. Genetically engineered BRCA1-deficient mouse models offer a unique opportunit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hámori, Lilla, Kudlik, Gyöngyi, Szebényi, Kornélia, Kucsma, Nóra, Szeder, Bálint, Póti, Ádám, Uher, Ferenc, Várady, György, Szüts, Dávid, Tóvári, József, Füredi, András, Szakács, Gergely
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072850/
https://ncbi.nlm.nih.gov/pubmed/32053991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041185
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