Establishment and Characterization of a Brca1(−/−), p53(−/−) Mouse Mammary Tumor Cell Line

Breast cancer is the most commonly occurring cancer in women and the second most common cancer overall. By the age of 80, the estimated risk for breast cancer for women with germline BRCA1 or BRCA2 mutations is around 80%. Genetically engineered BRCA1-deficient mouse models offer a unique opportunit...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Hámori, Lilla, Kudlik, Gyöngyi, Szebényi, Kornélia, Kucsma, Nóra, Szeder, Bálint, Póti, Ádám, Uher, Ferenc, Várady, György, Szüts, Dávid, Tóvári, József, Füredi, András, Szakács, Gergely
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072850/
https://ncbi.nlm.nih.gov/pubmed/32053991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041185
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