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Establishment and Characterization of a Brca1(−/−), p53(−/−) Mouse Mammary Tumor Cell Line

Breast cancer is the most commonly occurring cancer in women and the second most common cancer overall. By the age of 80, the estimated risk for breast cancer for women with germline BRCA1 or BRCA2 mutations is around 80%. Genetically engineered BRCA1-deficient mouse models offer a unique opportunit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Hámori, Lilla, Kudlik, Gyöngyi, Szebényi, Kornélia, Kucsma, Nóra, Szeder, Bálint, Póti, Ádám, Uher, Ferenc, Várady, György, Szüts, Dávid, Tóvári, József, Füredi, András, Szakács, Gergely
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072850/
https://ncbi.nlm.nih.gov/pubmed/32053991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041185
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