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Poison-Exon Inclusion in DHX9 Reduces Its Expression and Sensitizes Ewing Sarcoma Cells to Chemotherapeutic Treatment

Alternative splicing is a combinatorial mechanism by which exons are joined to produce multiple mRNA variants, thus expanding the coding potential and plasticity of eukaryotic genomes. Defects in alternative splicing regulation are associated with several human diseases, including cancer. Ewing sarc...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cells
Main Authors: Palombo, Ramona, Verdile, Veronica, Paronetto, Maria Paola
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072589/
https://ncbi.nlm.nih.gov/pubmed/32023846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020328
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