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Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer

Head and neck squamous cell carcinomas (HNSCC) affect more than 800,000 people annually worldwide, causing over 15,000 deaths in the US. Among HNSCC cancers, human papillomavirus (HPV)-negative HNSCC has the worst outcome, motivating efforts to improve therapy for this disease. The most common mutat...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Deneka, Alexander Y., Einarson, Margret B., Bennett, John, Nikonova, Anna S., Elmekawy, Mohamed, Zhou, Yan, Lee, Jong Woo, Burtness, Barbara A., Golemis, Erica A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072436/
https://ncbi.nlm.nih.gov/pubmed/32012873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020306
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