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Silencing of PARP2 Blocks Autophagic Degradation
Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD(+). PARP1 and PARP10 were previously implicated in the regulation of autophagy. Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA. The cytosolic el...
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| Publicado en: | Cells |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072353/ https://ncbi.nlm.nih.gov/pubmed/32046043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020380 |
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