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Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age
Transcription of the ribosomal RNA genes (rDNA) that encode the three largest ribosomal RNAs (rRNA), is mediated by RNA Polymerase I (Pol I) and is a key regulatory step for ribosomal biogenesis. Although it has been reported over a century ago that the number and size of nucleoli, the site of ribos...
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| Veröffentlicht in: | Cells |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072222/ https://ncbi.nlm.nih.gov/pubmed/31973211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020266 |
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