Dephosphorylation of YB-1 is Required for Nuclear Localisation During G(2) Phase of the Cell Cycle

Elevated levels of nuclear Y-box binding protein 1 (YB-1) are linked to poor prognosis in cancer. It has been proposed that entry into the nucleus requires specific proteasomal cleavage. However, evidence for cleavage is contradictory and high YB-1 levels are prognostic regardless of cellular locati...

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Publicado en:Cancers (Basel)
Main Authors: Mehta, Sunali, McKinney, Cushla, Algie, Michael, Verma, Chandra S., Kannan, Srinivasaraghavan, Harfoot, Rhodri, Bartolec, Tara K., Bhatia, Puja, Fisher, Alistair J., Gould, Maree L., Parker, Kim, Cesare, Anthony J., Cunliffe, Heather E., Cohen, Scott B., Kleffmann, Torsten, Braithwaite, Antony W., Woolley, Adele G.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072210/
https://ncbi.nlm.nih.gov/pubmed/32013098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020315
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