Dephosphorylation of YB-1 is Required for Nuclear Localisation During G(2) Phase of the Cell Cycle

Elevated levels of nuclear Y-box binding protein 1 (YB-1) are linked to poor prognosis in cancer. It has been proposed that entry into the nucleus requires specific proteasomal cleavage. However, evidence for cleavage is contradictory and high YB-1 levels are prognostic regardless of cellular locati...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mehta, Sunali, McKinney, Cushla, Algie, Michael, Verma, Chandra S., Kannan, Srinivasaraghavan, Harfoot, Rhodri, Bartolec, Tara K., Bhatia, Puja, Fisher, Alistair J., Gould, Maree L., Parker, Kim, Cesare, Anthony J., Cunliffe, Heather E., Cohen, Scott B., Kleffmann, Torsten, Braithwaite, Antony W., Woolley, Adele G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072210/
https://ncbi.nlm.nih.gov/pubmed/32013098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020315
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