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Activation of Astroglial Connexin Is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine

Clozapine (CLZ) is a gold-standard antipsychotic against treatment-refractory schizophrenia, but is one of the most toxic antipsychotic agents. Pharmacological mechanisms of the double-edged sword clinical action of CLZ remain to be clarified. To explore the mechanisms of CLZ, the present study dete...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Fukuyama, Kouji, Okubo, Ruri, Murata, Masahiko, Shiroyama, Takashi, Okada, Motohiro
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072131/
https://ncbi.nlm.nih.gov/pubmed/32054069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020414
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