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Mechanistic approaches for chemically modifying the coordination sphere of copper–amyloid-β complexes
Neurotoxic implications of the interactions between Cu(I/II) and amyloid-β (Aβ) indicate a connection between amyloid cascade hypothesis and metal ion hypothesis with respect to the neurodegeneration associated with Alzheimer’s disease (AD). Herein, we report a mechanistic strategy for modifying the...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7071886/ https://ncbi.nlm.nih.gov/pubmed/32102914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916944117 |
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