An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

BACKGROUND: Previous studies using candidate gene and genome-wide approaches have identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic stress disorder (PTSD). METHODS: In this study, we performed an EWAS of PTSD in a cohort of Veterans (n = 378 lifetime PTSD cases an...

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Publicado en:Clin Epigenetics
Main Authors: Logue, Mark W., Miller, Mark W., Wolf, Erika J., Huber, Bertrand Russ, Morrison, Filomene G., Zhou, Zhenwei, Zheng, Yuanchao, Smith, Alicia K., Daskalakis, Nikolaos P., Ratanatharathorn, Andrew, Uddin, Monica, Nievergelt, Caroline M., Ashley-Koch, Allison E., Baker, Dewleen G., Beckham, Jean C., Garrett, Melanie E., Boks, Marco P., Geuze, Elbert, Grant, Gerald A., Hauser, Michael A., Kessler, Ronald C., Kimbrel, Nathan A., Maihofer, Adam X., Marx, Christine E., Qin, Xue-Jun, Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Vinkers, Christiaan H., Ware, Erin B., Stone, Annjanette, Schichman, Steven A., McGlinchey, Regina E., Milberg, William P., Hayes, Jasmeet P., Verfaellie, Mieke
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071645/
https://ncbi.nlm.nih.gov/pubmed/32171335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0820-0
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