An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

BACKGROUND: Previous studies using candidate gene and genome-wide approaches have identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic stress disorder (PTSD). METHODS: In this study, we performed an EWAS of PTSD in a cohort of Veterans (n = 378 lifetime PTSD cases an...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Logue, Mark W., Miller, Mark W., Wolf, Erika J., Huber, Bertrand Russ, Morrison, Filomene G., Zhou, Zhenwei, Zheng, Yuanchao, Smith, Alicia K., Daskalakis, Nikolaos P., Ratanatharathorn, Andrew, Uddin, Monica, Nievergelt, Caroline M., Ashley-Koch, Allison E., Baker, Dewleen G., Beckham, Jean C., Garrett, Melanie E., Boks, Marco P., Geuze, Elbert, Grant, Gerald A., Hauser, Michael A., Kessler, Ronald C., Kimbrel, Nathan A., Maihofer, Adam X., Marx, Christine E., Qin, Xue-Jun, Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Vinkers, Christiaan H., Ware, Erin B., Stone, Annjanette, Schichman, Steven A., McGlinchey, Regina E., Milberg, William P., Hayes, Jasmeet P., Verfaellie, Mieke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071645/
https://ncbi.nlm.nih.gov/pubmed/32171335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0820-0
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