Chronic Chemogenetic Stimulation of the Nucleus Accumbens Produces Lasting Reductions in Binge Drinking and Ameliorates Alcohol-Related Morphological and Transcriptional Changes

Binge drinking is a dangerous pattern of behavior. We tested whether chronically manipulating nucleus accumbens (NAc) activity (via clozapine-N-oxide (CNO) and Designer Receptors Exclusively Activated by Designer Drugs (DREADD)) could produce lasting effects on ethanol binge-like drinking in mice se...

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Detalhes bibliográficos
Publicado no:Brain Sci
Main Authors: Pozhidayeva, Dar’ya Y., Farris, Sean P., Goeke, Calla M., Firsick, Evan J., Townsley, Kayla G., Guizzetti, Marina, Ozburn, Angela R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071376/
https://ncbi.nlm.nih.gov/pubmed/32085427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci10020109
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