Metronidazole and Secnidazole Carbamates: Synthesis, Antiprotozoal Activity, and Molecular Dynamics Studies

We prepared a series of 10 carbamates derivatives based on two common antiprotozoal drugs: metronidazole (1–5) and secnidazole (6–10). The compounds were tested in vitro against a set of two amitochondriate protozoa: Giardia duodenalis and Trichomonas vaginalis. Compounds 1–10 showed strong antiprot...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Rocha-Garduño, Genaro, Hernández-Martínez, Norma Angélica, Colín-Lozano, Blanca, Estrada-Soto, Samuel, Hernández-Núñez, Emanuel, Prieto-Martínez, Fernando Daniel, Medina-Franco, José L., Chale-Dzul, Juan Bautista, Moo-Puc, Rosa, Navarrete-Vázquez, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071106/
https://ncbi.nlm.nih.gov/pubmed/32059495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040793
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker