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Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with three isoforms (PPARα, PPARβ/δ, PPARγ) and can regulate pain, anxiety, and cognition. However, their role in conditioned fear and pain-fear interactions has not yet been investigated. Here, we investigated the effects of...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Gaspar, Jessica C., Okine, Bright N., Llorente-Berzal, Alvaro, Roche, Michelle, Finn, David P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070536/
https://ncbi.nlm.nih.gov/pubmed/32102354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25041007
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