A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats

Background and PurposeThe nuclear hormone receptor, PPARα, and its endogenous ligands, are involved in pain modulation. PPARα is expressed in the medial prefrontal cortex (mPFC), a key brain region involved in both the cognitive-affective component of pain and in descending modulation of pain. Howev...

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Bibliographic Details
Main Authors: Okine, B N, Rea, K, Olango, W M, Price, J, Herdman, S, Madasu, M K, Roche, M, Finn, D P
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
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Themed Section: Cannabinoids 2013
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954485/
https://ncbi.nlm.nih.gov/pubmed/24303983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12540
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