Synthesis and Cytotoxic Activity of New Vindoline Derivatives Coupled to Natural and Synthetic Pharmacophores

New Vinca alkaloid derivatives were synthesized to improve the biological activity of the natural alkaloid vindoline. To this end, experiments were performed to link vindoline with various structural units, such as amino acids, a 1,2,3-triazole derivative, morpholine, piperazine and N-methylpiperazi...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Keglevich, András, Dányi, Leonetta, Rieder, Alexandra, Horváth, Dorottya, Szigetvári, Áron, Dékány, Miklós, Szántay, Csaba, Latif, Ahmed Dhahir, Hunyadi, Attila, Zupkó, István, Keglevich, Péter, Hazai, László
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070384/
https://ncbi.nlm.nih.gov/pubmed/32102414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25041010
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