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Synthesis and Cytotoxic Activity of New Vindoline Derivatives Coupled to Natural and Synthetic Pharmacophores

New Vinca alkaloid derivatives were synthesized to improve the biological activity of the natural alkaloid vindoline. To this end, experiments were performed to link vindoline with various structural units, such as amino acids, a 1,2,3-triazole derivative, morpholine, piperazine and N-methylpiperazi...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Keglevich, András, Dányi, Leonetta, Rieder, Alexandra, Horváth, Dorottya, Szigetvári, Áron, Dékány, Miklós, Szántay, Csaba, Latif, Ahmed Dhahir, Hunyadi, Attila, Zupkó, István, Keglevich, Péter, Hazai, László
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070384/
https://ncbi.nlm.nih.gov/pubmed/32102414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25041010
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