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The mechanism of hsa-miR-424-5 combining PD-1 through mTORC signaling pathway to stimulate immune effect and participate in Type 1 diabetes

In the present study, hsa-miR-424-5p mimic plasmid and hsa-mir-424-5p inhibitor plasmid were designed and injected into rats respectively, and miRNA control plasmid was also constructed. Models of Type 1 diabetes (T1D) were built. After successful modeling, the expression of hsa-miR-424-5p in lympho...

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Détails bibliographiques
Publié dans:Biosci Rep
Auteurs principaux: Wang, Guofeng, Yan, Yongxin, Zheng, Zhichen, Zhang, Tongyu
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070146/
https://ncbi.nlm.nih.gov/pubmed/32010928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20193800
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