Model‐based data analysis of individual human postprandial plasma bile acid responses indicates a major role for the gallbladder and intestine

BACKGROUND: Bile acids are multifaceted metabolic compounds that signal to cholesterol, glucose, and lipid homeostasis via receptors like the Farnesoid X Receptor (FXR) and transmembrane Takeda G protein‐coupled receptor 5 (TGR5). The postprandial increase in plasma bile acid concentrations is there...

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Publicado en:Physiol Rep
Autores principales: Meessen, Emma C. E., Sips, Fianne L. P., Eggink, Hannah M., Koehorst, Martijn, Romijn, Johannes A., Groen, Albert K., van Riel, Natal A. W., Soeters, Maarten R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070101/
https://ncbi.nlm.nih.gov/pubmed/32170845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14358
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