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Model‐based data analysis of individual human postprandial plasma bile acid responses indicates a major role for the gallbladder and intestine

BACKGROUND: Bile acids are multifaceted metabolic compounds that signal to cholesterol, glucose, and lipid homeostasis via receptors like the Farnesoid X Receptor (FXR) and transmembrane Takeda G protein‐coupled receptor 5 (TGR5). The postprandial increase in plasma bile acid concentrations is there...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Meessen, Emma C. E., Sips, Fianne L. P., Eggink, Hannah M., Koehorst, Martijn, Romijn, Johannes A., Groen, Albert K., van Riel, Natal A. W., Soeters, Maarten R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070101/
https://ncbi.nlm.nih.gov/pubmed/32170845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14358
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