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Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
Prevailing insulin resistance and the resultant hyperglycemia elicits a compensatory response from pancreatic islet beta cells (β-cells) that involves increases in β-cell function and β-cell mass. However, the sustained metabolic stress eventually leads to β-cell failure characterized by severe β-ce...
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| Vydáno v: | Cell Death Dis |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070087/ https://ncbi.nlm.nih.gov/pubmed/32170115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2365-8 |
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