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MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro

Providing a conducive microenvironment is critical to increase survival of transplanted stem cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac regeneration in the diabetic heart. Understanding the molecular mechanisms of high glucose-induced stem cell death is i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yadav, Santosh K., Kambis, Tyler N., Kar, Sumit, Park, Song Y., Mishra, Paras K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070071/
https://ncbi.nlm.nih.gov/pubmed/32170070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2367-6
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