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An amber obligate active site-directed ligand evolution technique for phage display
Although noncanonical amino acids (ncAAs) were first incorporated into phage libraries through amber suppression nearly two decades ago, their application for use in drug discovery has been limited due to inherent library bias towards sense-containing phages. Here, we report a technique based on sup...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070036/ https://ncbi.nlm.nih.gov/pubmed/32170178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15057-7 |
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