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Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9
CRISPR-Cas9 has led to great advances in gene editing for a broad spectrum of applications. To further the utility of Cas9 there have been efforts to achieve temporal control over its nuclease activity. While different approaches have focused on regulation of CRISPR interference or editing in mammal...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070018/ https://ncbi.nlm.nih.gov/pubmed/32170140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15226-8 |
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