Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

Non-small cell lung cancer (NSCLC) is known to have poor patient outcomes due to development of resistance to chemotherapy agents and the EGFR inhibitors, which results in recurrence of highly aggressive lung tumors. Even with recent success in immunotherapy using the checkpoint inhibitors, addition...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bora-Singhal, Namrata, Mohankumar, Durairaj, Saha, Biswarup, Colin, Christelle M., Lee, Jennifer Y., Martin, Matthew W., Zheng, Xiaozhang, Coppola, Domenico, Chellappan, Srikumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069992/
https://ncbi.nlm.nih.gov/pubmed/32170113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61295-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados