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Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling

Designing and implementing synthetic biological pattern formation remains challenging due to underlying theoretical complexity as well as the difficulty of engineering multicellular networks biochemically. Here, we introduce a cell-in-the-loop approach where living cells interact through in silico s...

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Publicat a:Nat Commun
Autors principals: Perkins, Melinda Liu, Benzinger, Dirk, Arcak, Murat, Khammash, Mustafa
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069979/
https://ncbi.nlm.nih.gov/pubmed/32170129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15166-3
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