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An Optogenetic Platform for Real-Time, Single-Cell Interrogation of Stochastic Transcriptional Regulation

Transcription is a highly regulated and inherently stochastic process. The complexity of signal transduction and gene regulation makes it challenging to analyze how the dynamic activity of transcriptional regulators affects stochastic transcription. By combining a fast-acting, photo-regulatable tran...

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Foilsithe in:Mol Cell
Main Authors: Rullan, Marc, Benzinger, Dirk, Schmidt, Gregor W., Milias-Argeitis, Andreas, Khammash, Mustafa
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971206/
https://ncbi.nlm.nih.gov/pubmed/29775585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.012
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