Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor

MCFD2 and ERGIC-53, which are the products of causative genes of combined factor V and factor VIII deficiency, form a cargo receptor complex responsible for intracellular transport of these coagulation factors in the early secretory pathway. In this study, using an NMR technique, we successfully ide...

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Pubblicato in:Nat Commun
Autori principali: Yagi, Hirokazu, Yagi-Utsumi, Maho, Honda, Rena, Ohta, Yusaku, Saito, Taiki, Nishio, Miho, Ninagawa, Satoshi, Suzuki, Kousuke, Anzai, Takahiro, Kamiya, Yukiko, Aoki, Kazuhiro, Nakanishi, Mahito, Satoh, Tadashi, Kato, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069976/
https://ncbi.nlm.nih.gov/pubmed/32170195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15192-1
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