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Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity
Transcription factors (TFs) control cell fates by precisely orchestrating gene expression. However, how individual TFs promote transcriptional diversity remains unclear. Here, we use the Hox TF Ultrabithorax (Ubx) as a model to explore how a single TF specifies multiple cell types. Using proximity-d...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069958/ https://ncbi.nlm.nih.gov/pubmed/32170121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15223-x |
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