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Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

Transcription factors (TFs) control cell fates by precisely orchestrating gene expression. However, how individual TFs promote transcriptional diversity remains unclear. Here, we use the Hox TF Ultrabithorax (Ubx) as a model to explore how a single TF specifies multiple cell types. Using proximity-d...

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Publicat a:Nat Commun
Autors principals: Carnesecchi, Julie, Sigismondo, Gianluca, Domsch, Katrin, Baader, Clara Eva Paula, Rafiee, Mahmoud-Reza, Krijgsveld, Jeroen, Lohmann, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069958/
https://ncbi.nlm.nih.gov/pubmed/32170121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15223-x
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