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Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

Transcription factors (TFs) control cell fates by precisely orchestrating gene expression. However, how individual TFs promote transcriptional diversity remains unclear. Here, we use the Hox TF Ultrabithorax (Ubx) as a model to explore how a single TF specifies multiple cell types. Using proximity-d...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Carnesecchi, Julie, Sigismondo, Gianluca, Domsch, Katrin, Baader, Clara Eva Paula, Rafiee, Mahmoud-Reza, Krijgsveld, Jeroen, Lohmann, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069958/
https://ncbi.nlm.nih.gov/pubmed/32170121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15223-x
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