Cetuximab Conjugated with Octreotide and Entrapped Calcium Alginate-beads for Targeting Somatostatin Receptors

There is a need to formulate oral cetuximab (CTX) for targeting colorectal cancer, which is reported to express somatostatin receptors (SSTRs). Therefore, coating CTX with a somatostatin analogue such as octreotide (OCT) is beneficial. Alginate was used to coat CTX to facilitate delivery to the gast...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Abdellatif, Ahmed A. H., Ibrahim, Mohamed A., Amin, Mohammed A., Maswadeh, Hamzah, Alwehaibi, Muhammed N., Al-Harbi, Sultan N., Alharbi, Zayed A., Mohammed, Hamdoon A., Mehany, Ahmed B. M., Saleem, Imran
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069942/
https://ncbi.nlm.nih.gov/pubmed/32170176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61605-y
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