Paneth cell dysfunction mediates alcoholic steatohepatitis through promoting bacterial translocation in mice: role of zinc deficiency

Microbial dysbiosis is associated with alcoholic hepatitis (AH) with the mechanisms yet to be elucidated. The present study aimed to determine the effects of alcohol and zinc deficiency on Paneth cell (PC) antimicrobial peptides - α-defensins, and to define the link between PC dysfunction and AH. Tr...

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Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Zhong, Wei, Wei, Xiaoyuan, Hao, Liuyi, Lin, Tai-Du, Yue, Ruichao, Sun, Xinguo, Guo, Wei, Dong, Haibo, Li, Tianjiao, Ahmadi, Ali R., Sun, Zhaoli, Zhang, Qibin, Zhao, Jiangchao, Zhou, Zhanxiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069794/
https://ncbi.nlm.nih.gov/pubmed/31520476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30945
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