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Design of fast proteolysis-based signaling and logic circuits in mammalian cells
Cellular signal transduction is predominantly based on protein interactions and their posttranslational modifications, which enable a fast response to input signals. Due to difficulties in designing new unique protein–protein interactions, designed cellular logic has focused on transcriptional regul...
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| Veröffentlicht in: | Nat Chem Biol |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069760/ https://ncbi.nlm.nih.gov/pubmed/30531965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0181-6 |
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