In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Vascularized composite allotransplantation (VCA) encompasses face and limb transplantation, but as with organ transplantation, it requires lifelong regimens of immunosuppressive drugs to prevent rejection. To achieve donor-specific immune tolerance and reduce the need for systemic immunosuppression,...

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Udgivet i:Sci Adv
Main Authors: Fisher, James D., Zhang, Wensheng, Balmert, Stephen C., Aral, Ali M., Acharya, Abhinav P., Kulahci, Yalcin, Li, Jingjing, Turnquist, Heth R., Thomson, Angus W., Solari, Mario G., Gorantla, Vijay S., Little, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069700/
https://ncbi.nlm.nih.gov/pubmed/32201714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax8429
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