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In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Vascularized composite allotransplantation (VCA) encompasses face and limb transplantation, but as with organ transplantation, it requires lifelong regimens of immunosuppressive drugs to prevent rejection. To achieve donor-specific immune tolerance and reduce the need for systemic immunosuppression,...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Fisher, James D., Zhang, Wensheng, Balmert, Stephen C., Aral, Ali M., Acharya, Abhinav P., Kulahci, Yalcin, Li, Jingjing, Turnquist, Heth R., Thomson, Angus W., Solari, Mario G., Gorantla, Vijay S., Little, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069700/
https://ncbi.nlm.nih.gov/pubmed/32201714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax8429
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