In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Vascularized composite allotransplantation (VCA) encompasses face and limb transplantation, but as with organ transplantation, it requires lifelong regimens of immunosuppressive drugs to prevent rejection. To achieve donor-specific immune tolerance and reduce the need for systemic immunosuppression,...

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Publicado en:Sci Adv
Autores principales: Fisher, James D., Zhang, Wensheng, Balmert, Stephen C., Aral, Ali M., Acharya, Abhinav P., Kulahci, Yalcin, Li, Jingjing, Turnquist, Heth R., Thomson, Angus W., Solari, Mario G., Gorantla, Vijay S., Little, Steven R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069700/
https://ncbi.nlm.nih.gov/pubmed/32201714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax8429
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