Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and lung tissue deterioration. Given the high vascularity of the lung, von Willebrand factor (VWF), a central component of wound healing initiation, has previously been assessed in COPD. VWF processing,...

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發表在:Int J Chron Obstruct Pulmon Dis
Main Authors: Langholm, Lasse L, Rønnow, Sarah Rank, Sand, Jannie M B, Leeming, Diana Julie, Tal-Singer, Ruth, Miller, Bruce E, Vestbo, Jørgen, Karsdal, Morten A, Manon-Jensen, Tina
格式: Artigo
語言:Inglês
出版: Dove 2020
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069584/
https://ncbi.nlm.nih.gov/pubmed/32210548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S235673
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