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Exploring the Activation Mechanism of the mGlu5 Transmembrane Domain
As a class C GPCR and regulator of synaptic activity, mGlu5 is an attractive drug target, potentially offering treatment for several neurologic and psychiatric disorders. As little is known about the activation mechanism of mGlu5 at a structural level, potential of mean force calculations linked to...
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| Gepubliceerd in: | Front Mol Biosci |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069277/ https://ncbi.nlm.nih.gov/pubmed/32211419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00038 |
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