Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

Metabotropic glutamate receptors (mGluRs) are important drug targets because of their involvement in several neurological diseases. Among mGluRs, mGlu5 is a particularly high-profile target because its positive or negative allosteric modulation can potentially treat schizophrenia or anxiety and chro...

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Pubblicato in:Curr Neuropharmacol
Autori principali: Dalton, James A.R., Lans, Isaias, Rovira, Xavier, Malhaire, Fanny, Gómez-Santacana, Xavier, Pittolo, Silvia, Gorostiza, Pau, Llebaria, Amadeu, Goudet, Cyril, Pin, Jean-Philippe, Giraldo, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Science Publishers 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983757/
https://ncbi.nlm.nih.gov/pubmed/26391742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X13666150407231417
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