Molecular and immunological features of a prolonged exceptional responder with malignant pleural mesothelioma treated initially and rechallenged with pembrolizumab

BACKGROUND: This case represents an exceptional response to pembrolizumab in a patient with epithelioid mesothelioma with a further response on rechallenge. CASE PRESENTATION: A 77-year-old woman with advanced epithelioid mesothelioma extensively pretreated with chemotherapy demonstrated a prolonged...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Minchom, Anna, Yuan, Wei, Crespo, Mateus, Gurel, Bora, Figueiredo, Ines, Wotherspoon, Andrew, Miranda, Susana, Riisnaes, Ruth, Ferreira, Ana, Bertan, Claudia, Pereira, Rita, Clarke, Matt, Baker, Chloe, Ang, Joo Ern, Fotiadis, Nicos, Tunariu, Nina, Carreira, Suzanne, Popat, Sanjay, O'Brien, Mary, Banerji, Udai, de Bono, Johann, Lopez, Juanita
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069263/
https://ncbi.nlm.nih.gov/pubmed/32169873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000713
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