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Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer
BACKGROUND: Poly (ADP-ribose) polymerase inhibitors targeting BRCA1/2 mutations are available for treating patients with high-grade serous ovarian cancer. These treatments may be more appropriately directed to patients who might respond if the tumor tissue is additionally tested by next-generation s...
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| 發表在: | BMC Cancer |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069205/ https://ncbi.nlm.nih.gov/pubmed/32164585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6693-y |
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