Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer

BACKGROUND: Poly (ADP-ribose) polymerase inhibitors targeting BRCA1/2 mutations are available for treating patients with high-grade serous ovarian cancer. These treatments may be more appropriately directed to patients who might respond if the tumor tissue is additionally tested by next-generation s...

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Vydáno v:BMC Cancer
Hlavní autoři: Eoh, Kyung Jin, Kim, Hye Min, Lee, Jung-Yun, Kim, Sunghoon, Kim, Sang Wun, Kim, Young Tae, Nam, Eun Ji
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069205/
https://ncbi.nlm.nih.gov/pubmed/32164585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6693-y
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