Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

Rationale: Androgen receptor splice variant 7 (AR-V7) is a leading cause of the development of castration-resistant prostate cancer (CRPC). However, the regulation and function of AR-V7 at levels of post-translational modifications in prostate cancer therapy remain poorly understood. Here, we conduc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Theranostics
Egile Nagusiak: Liao, Yuning, Liu, Yuan, Xia, Xiaohong, Shao, Zhenlong, Huang, Chuyi, He, Jinchan, Jiang, Lili, Tang, Daolin, Liu, Jinbao, Huang, Hongbiao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069092/
https://ncbi.nlm.nih.gov/pubmed/32206096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41849
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