Effect of Nilotinib on Bleomycin-Induced Acute Lung Injury and Pulmonary Fibrosis in Mice

BACKGROUND: The tyrosine kinase inhibitor imatinib mesylate was developed as an inhibitor of the kinase activity of BCR-ABL. However, imatinib also has potent inhibitory activity against the platelet-derived growth factor receptor (PDGFR). Nilotinib is approved for treating patients with chronic mye...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Respiration
Hauptverfasser: Rhee, Chin Kook, Lee, Sang Haak, Yoon, Hyung Kyu, Kim, Seok Chan, Lee, Sook Young, Kwon, Soon Suk, Kim, Young Kyoon, Kim, Kwan Hyoung, Kim, Tae Jung, Kim, Jin Woo
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2011
Schlagworte:
Basic Science Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068797/
https://ncbi.nlm.nih.gov/pubmed/21659722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000327719
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