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Different anti-remodeling effect of nilotinib and fluticasone in a chronic asthma model

BACKGROUND/AIMS: Inhaled corticosteroids are the most effective treatment currently available for asthma, but their beneficial effect against airway remodeling is limited. The tyrosine kinase inhibitor nilotinib has inhibitory activity against c-kit and the platelet-derived growth factor receptor. W...

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Publicado en:Korean J Intern Med
Autores principales: Kang, Hye Seon, Rhee, Chin Kook, Lee, Hea Yon, Yoon, Hyoung Kyu, Kwon, Soon Seok, Lee, Sook Young
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Association of Internal Medicine 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094918/
https://ncbi.nlm.nih.gov/pubmed/27764539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2015.002
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